Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans

201621 citationsJournal Articlegold Open Access

Authors

Sean P. David · Stanford University

Ange Wang · Stanford University

Kristopher Kapphahn · Stanford University

Haley Hedlin · Stanford University

Manisha Desai · Stanford University

Michael T. Henderson · Stanford University

Lingyao Yang ·

Abstract

These results suggest that chromosome 15q25.1 variants are robustly associated with CPD and lung cancer in African-Americans and that the allelic dose effect of these polymorphisms on lung cancer risk is most pronounced in lighter smokers.

Topics & Keywords

Genetic Associations and Epidemiology BRCA gene mutations in cancer Nutrition, Genetics, and Disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: EBioMedicine

Volume 4, pp. 153-161

DOI: 10.1016/j.ebiom.2016.01.002

Field-Weighted Citation Impact: 4.50