Combination of Vancomycin and β-Lactam Therapy for Methicillin-Resistant<i>Staphylococcus aureus</i>Bacteremia: A Pilot Multicenter Randomized Controlled Trial

2015181 citationsJournal Articlebronze Open Access

Authors

Joshua S. Davis · Menzies School of Health Research

Archana Sud · The University of Sydney

Matthew O’Sullivan · The University of Sydney

James O. Robinson · Curtin University

Patricia E. Ferguson · Blacktown & Mount Druitt Hospital

Hong Foo · Liverpool Hospital

Sebastiaan J. van Hal

Abstract

Combining an antistaphylococcal β-lactam with vancomycin may shorten the duration of MRSA bacteremia. Further trials with a larger sample size and objective clinically relevant end points are warranted. Australian New Zealand Clinical Trials Registry: ACTRN12610000940077 (www.anzctr.org.au).

Topics & Keywords

Antimicrobial Resistance in Staphylococcus Bacterial Identification and Susceptibility Testing Antibiotics Pharmacokinetics and Efficacy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

Volume 62, Issue 2, pp. 173-180

DOI: 10.1093/cid/civ808

Field-Weighted Citation Impact: 8.93