Metformin versus Placebo in Obese Pregnant Women without Diabetes Mellitus

2016385 citationsJournal Article

Authors

Argyro Syngelaki · King's College Hospital

K. H. Nicolaides · King's College Hospital

Jyoti Balani · Epsom and St Helier University Hospitals NHS Trust

Steve Hyer · Epsom and St Helier University Hospitals NHS Trust

Ranjit Akolekar · Harris Birthright Research Centre for Fetal Medicine

Reena Kotecha · King's College Hospital

Alice Pastides

Abstract

Among women without diabetes who had a BMI of more than 35, the antenatal administration of metformin reduced maternal weight gain but not neonatal birth weight. (Funded by the Fetal Medicine Foundation; ClinicalTrials.gov number, NCT01273584; EudraCT number, 2008-005892-83.).

Topics & Keywords

Gestational Diabetes Research and Management Bariatric Surgery and Outcomes Pregnancy and preeclampsia studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 374, Issue 5, pp. 434-443

DOI: 10.1056/nejmoa1509819

Field-Weighted Citation Impact: 65.59