Catechol-O-Methyltransferase Val158Met Polymorphism and Clinical Response to Antipsychotic Treatment in Schizophrenia and Schizo-Affective Disorder Patients: a Meta-Analysis

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Authors

Eric Yi‐Hsiu Huang · Centre for Addiction and Mental Health

Clement C. Zai · Centre for Addiction and Mental Health

Amanda Lisoway · Centre for Addiction and Mental Health

Małgorzata Maciukiewicz · Centre for Addiction and Mental Health

Daniel Felsky · Centre for Addiction and Mental Health

Arun K. Tiwari · Centre for Addiction and Mental Health

Jeffrey R. Bishop

Abstract

Our findings suggest that the COMT Val158Met polymorphism is associated with response to antipsychotics in schizophrenia and schizo-affective disorder patients. This effect may be more pronounced for atypical antipsychotics.

Topics & Keywords

Schizophrenia research and treatment Bipolar Disorder and Treatment Attention Deficit Hyperactivity Disorder

Publication Details

Published in: The International Journal of Neuropsychopharmacology

Volume 19, Issue 5, pp. pyv132-pyv132

DOI: 10.1093/ijnp/pyv132

Field-Weighted Citation Impact: 6.94

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Catechol-O-Methyltransferase Val158Met Polymorphism and Clinical Response to Antipsychotic Treatment in Schizophrenia and Schizo-Affective Disorder Patients: a Meta-Analysis

Authors

Abstract

Topics & Keywords

Publication Details