Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory <i>N</i>-Arylation

2015132 citationsJournal Article

Authors

Suguru Yoshida · Tokyo Medical and Dental University

Takahisa Yano · Tokyo Medical and Dental University

Yoshihiro Misawa · Tokyo Medical and Dental University

Yasuyuki Sugimura · Tokyo Medical and Dental University

Kazunobu Igawa · Kyushu University

Shigeomi Shimizu · Tokyo Medical and Dental University

Katsuhiko Tomooka

Abstract

A novel method for preparing a diverse range of o-sulfanylanilines is described. Direct thioamination of arynes with sulfilimines gives o-sulfanylanilines, involving C-N and C-S bond formations and migratory N-arylation.

Topics & Keywords

Cyclization and Aryne Chemistry Chemical synthesis and alkaloids Synthesis and pharmacology of benzodiazepine derivatives

Publication Details

Published in: Journal of the American Chemical Society

Volume 137, Issue 44, pp. 14071-14074

DOI: 10.1021/jacs.5b10557

Field-Weighted Citation Impact: 7.89

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Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory <i>N</i>-Arylation

Authors

Abstract

Topics & Keywords

Publication Details