Identification of Niclosamide as a Novel Anticancer Agent for Adrenocortical Carcinoma

201697 citationsJournal Article

Authors

Kei Satoh · Icahn School of Medicine at Mount Sinai

Lisa Zhang

Abstract

Our findings suggest that niclosamide has anti-ACC activity through its inhibition of multiple altered cellular pathways and cellular metabolism in ACC. Our results provide a preclinical rationale for evaluating niclosamide therapy in a clinical trial for ACC. Clin Cancer Res; 22(14); 3458-66. ©2016 AACR.

Topics & Keywords

Adrenal and Paraganglionic Tumors Cancer, Hypoxia, and Metabolism Glioma Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 22, Issue 14, pp. 3458-3466

DOI: 10.1158/1078-0432.ccr-15-2256

Field-Weighted Citation Impact: 10.04