Macrolide antibiotics and the risk of ventricular arrhythmia in older adults

2016149 citationsJournal Articlegold Open Access

Authors

Mai H. Trac · Lawson Health Research Institute

Eric McArthur · Institute for Clinical Evaluative Sciences

Racquel Jandoc · London Health Sciences Centre

Stephanie N. Dixon · Institute for Clinical Evaluative Sciences

Danielle M. Nash · Western University

Daniel G. Hackam · Lawson Health Research Institute

Amit X. Garg

Abstract

Among older adults, macrolide antibiotics were not associated with a higher 30-day risk of ventricular arrhythmia than nonmacrolide antibiotics. These findings suggest that current warnings from the US Food and Drug Administration may be overstated.

Topics & Keywords

Health Systems, Economic Evaluations, Quality of Life Cardiac electrophysiology and arrhythmias Pharmacovigilance and Adverse Drug Reactions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Canadian Medical Association Journal

Volume 188, Issue 7, pp. E120-E129

DOI: 10.1503/cmaj.150901

Field-Weighted Citation Impact: 60.33