Effect of Adherence to Oral Anticoagulants on Risk of Stroke and Major Bleeding Among Patients With Atrial Fibrillation

2016450 citationsJournal Articlegold Open Access

Authors

Xiaoxi Yao · Mayo Clinic in Arizona

Neena S. Abraham · Mayo Clinic

G. Caleb Alexander · Johns Hopkins University

William H. Crown · Optum (United States)

Víctor M. Montori · Mayo Clinic

Lindsey R. Sangaralingham · Mayo Clinic in Arizona

Bernard J. Gersh ·

Abstract

Adherence to anticoagulation is poor in practice and may be modestly improved with NOACs. Adherence to therapy appears to be most important in patients with CHA2DS2-VASc score ≥2, whereas the benefits of anticoagulation may not outweigh the harms in patients with CHA2DS2-VASc score 0 or 1.

Topics & Keywords

Atrial Fibrillation Management and Outcomes Cardiac Arrhythmias and Treatments Venous Thromboembolism Diagnosis and Management

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Journal of the American Heart Association

Volume 5, Issue 2

DOI: 10.1161/jaha.115.003074

Field-Weighted Citation Impact: 47.76