Plasma Branched-Chain Amino Acids and Incident Cardiovascular Disease in the PREDIMED Trial

2016285 citationsJournal Articlegreen Open Access

Authors

Miguel Ruiz‐Canela · Universidad de Navarra

Estefanía Toledo · Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition

Clary B. Clish · Broad Institute

Adela Hruby

Liming Liang · Cancer Research And Biostatistics

Jordi Salas‐Salvadó · Institut d'Investigació Sanitària Pere Virgili

Cristina Razquín · Universidad de Navarra

Abstract

Higher concentrations of baseline BCAAs were associated with increased risk of CVD, especially stroke, in a high cardiovascular risk population. A Mediterranean-style diet had a negligible effect on 1-year changes in BCAAs, but it may counteract the harmful effects of BCAAs on stroke.

Topics & Keywords

Nutritional Studies and Diet Metabolomics and Mass Spectrometry Studies Diet and metabolism studies

UN Sustainable Development Goals

Life below water

Publication Details

Published in: Clinical Chemistry

Volume 62, Issue 4, pp. 582-592

DOI: 10.1373/clinchem.2015.251710

Field-Weighted Citation Impact: 19.97