Genetic predisposition to ductal carcinoma in situ of the breast

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Authors

Christos Petridis · Guy's Hospital

Mark N. Brook · Institute of Cancer Research

Vandna Shah · Guy's Hospital

Kelly Kohut · Queen Mary University of London

Patricia Gorman · Queen Mary University of London

Michele Caneppele · Queen Mary University of London

Dina Levi ·

Abstract

In conclusion, this study provides the strongest evidence to date of a shared genetic susceptibility for IDC and DCIS. Studies with larger numbers of DCIS are needed to determine if IDC or DCIS specific loci exist.

Topics & Keywords

BRCA gene mutations in cancer Genetic Associations and Epidemiology Genomic variations and chromosomal abnormalities

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Breast Cancer Research

Volume 18, Issue 1, pp. 22-22

DOI: 10.1186/s13058-016-0675-7

Field-Weighted Citation Impact: 7.51