Human bone marrow-derived and umbilical cord-derived mesenchymal stem cells for alleviating neuropathic pain in a spinal cord injury model

2016154 citationsJournal Articlegold Open Access

Authors

Mahmoud Yousefifard · Tehran University of Medical Sciences

Farinaz Nasirinezhad · Iran University of Medical Sciences

Homa Manaheji · Shahid Beheshti University of Medical Sciences

Atousa Janzadeh · Iran University of Medical Sciences

Mostafa Hosseini · Tehran University of Medical Sciences

Mansoor Keshavarz · Tehran University of Medical Sciences

Abstract

The results of the present study show that BM-MSC and UC-MSC transplantations alleviated the symptoms of neuropathic pain and resulted in subsequent motor recovery after SCI. However, survival rate and electrophysiological findings of UC-MSC were significantly better than BM-MSC.

Topics & Keywords

Nerve injury and regeneration Spinal Cord Injury Research Mesenchymal stem cell research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Stem Cell Research & Therapy

Volume 7, Issue 1, pp. 36-36

DOI: 10.1186/s13287-016-0295-2

Field-Weighted Citation Impact: 7.71