An Injectable Self‐Assembling Collagen–Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy

2016794 citationsJournal Articlegreen Open Access

Authors

Ruirui Xing · Yanshan University

Kai Liu · University of Chinese Academy of Sciences

Tifeng Jiao · Yanshan University

Ning Zhang · Institute of Process Engineering

Kai Ma · Yanshan University

Ruiyun Zhang · Yanshan University

Qianli Zou ·

Abstract

An injectable and self-healing collagen-gold hybrid hydrogel is spontaneously formed by electrostatic self-assembly and subsequent biomineralization. It is demonstrated that such collagen-based hydrogels may be used as an injectable material for local delivery of therapeutic agents, showing enhanced antitumor efficacy.

Topics & Keywords

Collagen: Extraction and Characterization Silk-based biomaterials and applications Supramolecular Self-Assembly in Materials

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Advanced Materials

Volume 28, Issue 19, pp. 3669-3676

DOI: 10.1002/adma.201600284

Field-Weighted Citation Impact: 63.02