Co-location of the oxazolidinone resistance genes<i>optrA</i>and<i>cfr</i>on a multiresistance plasmid from<i>Staphylococcus sciuri</i>

This is the first report of the optrA gene in staphylococci and of the coexistence of optrA and cfr on the same plasmid. Dissemination of this plasmid will substantially limit the efficacy of oxazolidinones. Surveillance of optrA in staphylococci of both human and animal origin is urgently warranted.