Silent cerebral infarcts and cerebral aneurysms are prevalent in adults with sickle cell anemia

2016153 citationsJournal Articlebronze Open Access

Authors

Adetola A. Kassim

Sumit Pruthi

Matthew Day · Vanderbilt University Medical Center

Mark Rodeghier

Melissa C. Gindville · Vanderbilt University Medical Center

Max Brodsky · Drexel University

Michael R. DeBaun

Lori C. Jordan · Vanderbilt University Medical Center

Abstract

To the editor: Silent cerebral infarcts (SCIs) are the most commonly recognized cause of neurologic injury in patients with sickle cell anemia (SCA), identified in ≥20% of children. In children with SCA, SCIs are associated with an average 5 full-scale IQ point decrement,[1][1] poor academic

Topics & Keywords

Hemoglobinopathies and Related Disorders Neurological Complications and Syndromes Folate and B Vitamins Research

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Blood

Volume 127, Issue 16, pp. 2038-2040

DOI: 10.1182/blood-2016-01-694562

Field-Weighted Citation Impact: 7.77