Effect of Surgery on Pancreatic Tumor-Dependent Lymphocyte Asset

201541 citationsJournal Articlehybrid Open Access

Authors

Francesco Iannone · Italian Institute of Technology

Alessandra Porzia · Italian Institute of Technology

Giovanna Peruzzi · Italian Institute of Technology

Patrizia Birarelli · Italian Institute of Technology

Bernardina Milana · Italian Institute of Technology

Luca Sacco · Italian Institute of Technology

Giuseppe Dinatale

Abstract

The NK cell functional ability is altered in presurgery patients; duodenopancreatectomy is associated with short-term impairment of NK function and with a long-term NK cell augmentation and reversion of the aberrant NK behavior, which may impact on immunosurveillance against residual cancer.

Topics & Keywords

Immune Cell Function and Interaction Cancer Immunotherapy and Biomarkers Gastrointestinal Tumor Research and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pancreas

Volume 44, Issue 3, pp. 386-393

DOI: 10.1097/mpa.0000000000000288

Field-Weighted Citation Impact: 0.83