Clinical Significance of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia

1998773 citationsJournal Articlebronze Open Access

Authors

Hélène Cavé · Laboratoire de Biochimie

Jutte van der Werff ten Bosch · Vrije Universiteit Brussel

Stefan Suciu · European Organisation for Research and Treatment of Cancer

C Guidal · Hôpital Robert-Debré

C Waterkeyn · European Organisation for Research and Treatment of Cancer

J. Otten · Universitair Ziekenhuis Brussel

Marleen Bâkkus

Abstract

Residual leukemia after induction of a remission is a powerful prognostic factor in childhood ALL. Detection of residual disease by PCR should be used to identify patients at risk for relapse and should be taken into account in considering alternative treatment.

Topics & Keywords

Acute Lymphoblastic Leukemia research Chronic Lymphocytic Leukemia Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 339, Issue 9, pp. 591-598

DOI: 10.1056/nejm199808273390904

Field-Weighted Citation Impact: 59.62