Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma

19993,037 citationsJournal Article

Authors

Jesper Lagergren · Karolinska Institutet

Abstract

There is a strong and probably causal relation between gastroesophageal reflux and esophageal adenocarcinoma. The relation between reflux and adenocarcinoma of the gastric cardia is relatively weak.

Topics & Keywords

Esophageal Cancer Research and Treatment Gastroesophageal reflux and treatments Helicobacter pylori-related gastroenterology studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 340, Issue 11, pp. 825-831

DOI: 10.1056/nejm199903183401101

Field-Weighted Citation Impact: 137.12