Antitumor Activity of Thalidomide in Refractory Multiple Myeloma

19992,581 citationsJournal Articlebronze Open Access

Authors

Seema Singhal · University of South Carolina

Jayesh Mehta · University of South Carolina

Raman Desikan · University of Arkansas for Medical Sciences

Dan Ayers · University of Arkansas for Medical Sciences

Paula K. Roberson · University of Arkansas for Medical Sciences

Paul Eddlemon · University of Arkansas for Medical Sciences

Nikhil C. Munshi

Abstract

Thalidomide is active against advanced myeloma. It can induce marked and durable responses in some patients with multiple myeloma, including those who relapse after high-dose chemotherapy.

Topics & Keywords

Multiple Myeloma Research and Treatments Cancer Treatment and Pharmacology Protein Degradation and Inhibitors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 341, Issue 21, pp. 1565-1571

DOI: 10.1056/nejm199911183412102

Field-Weighted Citation Impact: 57.52