Survival in Medically Treated Patients with Homozygous β-Thalassemia

1994864 citationsJournal Articlebronze Open Access

Authors

Nancy F. Olivieri · Toronto General Hospital

David G. Nathan · Children's Hospital of Philadelphia

James H. MacMillan · SickKids Foundation

Alan S. Wayne · Harvard University

Peter P. Liu · University of Toronto

Allison McGee · Hospital for Sick Children

Marie Martin ·

Abstract

The prognosis for survival without cardiac disease is excellent for patients with thalassemia major who receive regular transfusions and whose serum ferritin concentrations remain below 2500 ng per milliliter with chelation therapy.

Topics & Keywords

Hemoglobinopathies and Related Disorders Iron Metabolism and Disorders Erythropoietin and Anemia Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 331, Issue 9, pp. 574-578

DOI: 10.1056/nejm199409013310903

Field-Weighted Citation Impact: 11.93