A Trial of Goal-Oriented Hemodynamic Therapy in Critically Ill Patients

19951,518 citationsJournal Articlebronze Open Access

Authors

Luciano Gattinoni · Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Luca Brazzi · Ospedale Maggiore

Paolo Pelosi · Ospedale Maggiore

Roberto Latini · Mario Negri Institute for Pharmacological Research

Gianni Tognoni · Mario Negri Institute for Pharmacological Research

Antonio Pesenti · Azienda Ospedaliera San Gerardo

Roberto Fumagalli

Abstract

Hemodynamic therapy aimed at achieving supranormal values for the cardiac index or normal values for mixed venous oxygen saturation does not reduce morbidity or mortality among critically ill patients.

Topics & Keywords

Hemodynamic Monitoring and Therapy Sepsis Diagnosis and Treatment Cardiac, Anesthesia and Surgical Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 333, Issue 16, pp. 1025-1032

DOI: 10.1056/nejm199510193331601

Field-Weighted Citation Impact: 64.64