The Effect of Corticosteroids for Acute Optic Neuritis on the Subsequent Development of Multiple Sclerosis

1993584 citationsJournal Articlebronze Open Access

Authors

Roy W. Beck · Jaeb Center for Health Research

Patricia A. Cleary

Jonathan D. Trobe · W.K. Kellogg Foundation

David I. Kaufman · Michigan State University

Mark J. Kupersmith · New York University

Donald W. Paty · University of British Columbia

C. Hendricks Brown · University of South Florida

Abstract

In patients with acute optic neuritis, treatment with a three-day course of high-dose intravenous methylprednisolone (followed by a short course of prednisone) reduces the rate of development of multiple sclerosis over a two-year period.

Topics & Keywords

Multiple Sclerosis Research Studies Peripheral Neuropathies and Disorders Rheumatoid Arthritis Research and Therapies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 329, Issue 24, pp. 1764-1769

DOI: 10.1056/nejm199312093292403

Field-Weighted Citation Impact: 18.40