Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves

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Authors

Raj Makkar

Gregory P. Fontana · Cedars-Sinai Medical Center

Hasan Jilaihawi

Tarun Chakravarty

Klaus F. Kofoed · University of Copenhagen

Ole De Backer · University of Copenhagen

Federico M. Asch · MedStar Health

Carlos E. Ruiz

Niels Thue Olsen

Abstract

Reduced aortic-valve leaflet motion was shown in patients with bioprosthetic aortic valves. The condition resolved with therapeutic anticoagulation. The effect of this finding on clinical outcomes including stroke needs further investigation. (Funded by St. Jude Medical and Cedars-Sinai Heart Institute; Portico-IDE ClinicalTrials.gov number, NCT02000115; SAVORY registry, NCT02426307; and RESOLVE registry, NCT02318342.).

Topics & Keywords

Cardiac Valve Diseases and Treatments Infective Endocarditis Diagnosis and Management Aortic Disease and Treatment Approaches

Publication Details

Published in: New England Journal of Medicine

Volume 373, Issue 21, pp. 2015-2024

DOI: 10.1056/nejmoa1509233

Field-Weighted Citation Impact: 91.87

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Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves

Authors

Abstract

Topics & Keywords

Publication Details