Cumulative Meta-Analysis of Therapeutic Trials for Myocardial Infarction

19921,149 citationsJournal Articlebronze Open Access

Authors

Joseph Lau · Tufts Medical Center

Elliott M. Antman · Harvard University

Jeanette Jimenez-Silva

Bruce Kupelnick

Frederick Mosteller · Harvard University

Thomas C. Chalmers

Abstract

Cumulative meta-analysis of therapeutic trials facilitates the determination of clinical efficacy and harm and may be helpful in tracking trials, planning future trials, and making clinical recommendations for therapy.

Topics & Keywords

Meta-analysis and systematic reviews Statistical Methods in Clinical Trials Health Systems, Economic Evaluations, Quality of Life

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 327, Issue 4, pp. 248-254

DOI: 10.1056/nejm199207233270406

Field-Weighted Citation Impact: 104.72