A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension

19962,685 citationsJournal Articlebronze Open Access

Authors

Robyn J. Barst · Columbia University

Lewis J. Rubin · University of Maryland, Baltimore

Walker Long · University of North Carolina at Chapel Hill

Michael D. McGoon

Stuart Rich · University of Illinois Chicago

David B. Badesch · University of Colorado Health

Bertron Μ. Groves · University of Colorado Health

Abstract

As compared with conventional therapy, the continuous intravenous infusion of epoprostenol produced symptomatic and hemodynamic improvement, as well as improved survival in patients with severe primary pulmonary hypertension.

Topics & Keywords

Pulmonary Hypertension Research and Treatments Peptidase Inhibition and Analysis Heart Failure Treatment and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 334, Issue 5, pp. 296-301

DOI: 10.1056/nejm199602013340504

Field-Weighted Citation Impact: 70.66