Blood metabolomics analysis identifies abnormalities in the citric acid cycle, urea cycle, and amino acid metabolism in bipolar disorder

201698 citationsJournal Articlehybrid Open Access

Authors

Noriko Yoshimi · Center for Forensic Mental Health, Chiba University

Takashi Futamura · Otsuka (Japan)

Keiji Kakumoto · Otsuka (Japan)

Alireza M. Salehi · Karolinska Institutet

Carl M. Sellgren · Center for Human Genetics

Jessica Holmén‐Larsson · University of Gothenburg

Joel Jakobsson

Abstract

The present findings suggest that abnormalities in the citric acid cycle, urea cycle, and amino acid metabolism play a role in the pathogenesis of BD.

Topics & Keywords

Bipolar Disorder and Treatment Tryptophan and brain disorders Electrolyte and hormonal disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BBA Clinical

Volume 5, pp. 151-158

DOI: 10.1016/j.bbacli.2016.03.008

Field-Weighted Citation Impact: 7.24