Effect of Immunization with a Common Recall Antigen on Viral Expression in Patients Infected with Human Immunodeficiency Virus Type 1

1996375 citationsJournal Articlebronze Open Access

Authors

Sharilyn K. Stanley · National Institute of Allergy and Infectious Diseases

Mario Ostrowski · National Institute of Allergy and Infectious Diseases

J. Shawn Justement · National Institute of Allergy and Infectious Diseases

Kira R. Gantt · National Institute of Allergy and Infectious Diseases

S. Susan Hedayati · National Institute of Allergy and Infectious Diseases

Margaret L. Mannix · Cardinal Glennon Children’s Medical Center

Abstract

Activation of the immune system by an ongoing antigen-specific immune response to an exogenous stimulus transiently increases the expression of HIV-1 and may enhance the susceptibility of uninfected subjects to HIV-1.

Topics & Keywords

HIV Research and Treatment HIV/AIDS Research and Interventions HIV/AIDS drug development and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 334, Issue 19, pp. 1222-1229

DOI: 10.1056/nejm199605093341903

Field-Weighted Citation Impact: 12.07