Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

19943,771 citationsJournal Articlebronze Open Access

Authors

Lloyd Paul Aiello · Harvard University

Robert L. Avery · University of California, Santa Barbara

Paul G. Arrigg · Harvard University

Bruce A. Keyt

Henry Jampel · Johns Hopkins Hospital

Sabera T. Shah · Harvard University

Louis R. Pasquale · Brigham and Women's Hospital

Abstract

Our data suggest that VEGF plays a major part in mediating active intraocular neovascularization in patients with ischemic retinal diseases, such as diabetic retinopathy and retinal-vein occlusion.

Topics & Keywords

Retinal Diseases and Treatments Glaucoma and retinal disorders Angiogenesis and VEGF in Cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 331, Issue 22, pp. 1480-1487

DOI: 10.1056/nejm199412013312203

Field-Weighted Citation Impact: 88.20