Fludarabine Compared with Chlorambucil as Primary Therapy for Chronic Lymphocytic Leukemia

20001,002 citationsJournal Articlebronze Open Access

Authors

R. Kanti · Leukemia Research Foundation

Bercedis L. Peterson

Frederick R. Appelbaum

Abstract

When used as the initial treatment for chronic lymphocytic leukemia, fludarabine yields higher response rates and a longer duration of remission and progression-free survival than chlorambucil.

Topics & Keywords

Chronic Lymphocytic Leukemia Research Lymphoma Diagnosis and Treatment Immunodeficiency and Autoimmune Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 343, Issue 24, pp. 1750-1757

DOI: 10.1056/nejm200012143432402

Field-Weighted Citation Impact: 32.16