Liposomal Amphotericin B for Empirical Therapy in Patients with Persistent Fever and Neutropenia

19991,201 citationsJournal Articlebronze Open Access

Authors

Thomas J. Walsh · National Cancer Institute

Robert W. Finberg

Abstract

Liposomal amphotericin B is as effective as conventional amphotericin B for empirical antifungal therapy in patients with fever and neutropenia, and it is associated with fewer breakthrough fungal infections, less infusion-related toxicity, and less nephrotoxicity.

Topics & Keywords

Neutropenia and Cancer Infections Bacterial Identification and Susceptibility Testing Hematological disorders and diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 340, Issue 10, pp. 764-771

DOI: 10.1056/nejm199903113401004

Field-Weighted Citation Impact: 28.47