A Comparative Study of Blood Volume in Dogs

Conclusion1. A comparison of 3 methods for the determination of blood volume was made on 10 dogs. 2. The average blood volumes expressed as per cent of body weight for the 3 methods were: T-1824, 10.5%; for red cells tagged with P32, 9.7%; and iodinated protein, 9.4%. 3. The iodinated protein method permitted accurate determinations of plasma volumes for a much longer period after injection than did the other two methods. This method was simple and direct. It permitted calculation of the volume within a few minutes after the samples were obtained. It appeared to have a decided advantage over blood volume estimation with P32 impregnated red blood cells and the T-1824 dye method.