Association of Intergenic Polymorphism of Organic Anion Transporter 1 and 3 Genes With Hypertension and Blood Pressure Response to Hydrochlorothiazide

201039 citationsJournal Articlebronze Open Access

Authors

Y.-F. Han · The Military General Hospital of Beijing PLA

Xiaoxu Fan · Chinese Academy of Medical Sciences & Peking Union Medical College

X.-J. Wang · Chinese Academy of Medical Sciences & Peking Union Medical College

K. Sun · Chinese Academy of Medical Sciences & Peking Union Medical College

Hao Xue · Chinese Academy of Medical Sciences & Peking Union Medical College

Wan‐Ju Li · Chinese Academy of Medical Sciences & Peking Union Medical College

Abstract

Intergenic polymorphism rs10792367 between OAT1 and OAT3 is not associated with hypertension, but appears to be involved in between-individual variations in antihypertensive responses to HCTZ.

Topics & Keywords

Drug Transport and Resistance Mechanisms Ion Transport and Channel Regulation Renal function and acid-base balance

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Hypertension

Volume 24, Issue 3, pp. 340-346

DOI: 10.1038/ajh.2010.191

Field-Weighted Citation Impact: 1.78