Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction

2016137 citationsJournal Articlebronze Open Access

Authors

Tingting Chen

Caroline Blanc

Anke Z. Eder

Rafael Prados‐Rosales

Ana Camila Oliveira Souza

Ryung S. Kim · Albert Einstein College of Medicine

Aharona Glatman‐Freedman · New York Medical College

Maju Joe · University of Alberta

Yu Bai · University of Alberta

Abstract

Our results provide further evidence for a role of Ab-mediated immunity to tuberculosis and suggest that IgG to AM, especially to some of its OS epitopes, could contribute to the defense against mycobacterial infection in humans.

Topics & Keywords

Immunodeficiency and Autoimmune Disorders Mycobacterium research and diagnosis Carbohydrate Chemistry and Synthesis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Infectious Diseases

Volume 214, Issue 2, pp. 300-310

DOI: 10.1093/infdis/jiw141

Field-Weighted Citation Impact: 7.62