HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients

2016745 citationsJournal Articlegreen Open Access

Authors

Xavier Castellsagué · University Hospital Heidelberg

Laia Alemany · Institut Català d'Oncologia

Miquel Quer · Institut Català d'Oncologia

Gordana Halec · Institut Català d'Oncologia

Beatriz Quirós · Heidelberg University

Sara Tous · Heidelberg University

Omar Clavero ·

Abstract

HPV contribution to HNCs is substantial but highly heterogeneous by cancer site, region, and sex. This study, the largest exploring HPV attribution in HNCs, confirms the important role of HPVs in oropharyngeal cancer and drastically downplays the previously reported involvement of HPVs in the other HNCs.

Topics & Keywords

Head and Neck Cancer Studies Cervical Cancer and HPV Research Oral Health Pathology and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 108, Issue 6, pp. djv403-djv403

DOI: 10.1093/jnci/djv403

Field-Weighted Citation Impact: 73.21