Local Pathology and Systemic Serum Bupivacaine After Subcutaneous Delivery of Slow-Releasing Bupivacaine Microspheres

201414 citationsJournal Article

Authors

Birgitta Schmidt · Boston Children's Hospital

Rachit Ohri · Clinical Solutions

Jeffrey Chi-Fei Wang · Brigham and Women's Hospital

Phillip D. Blaskovich · Clinical Solutions

Allen Kesselring · Analytical Processes Engineered Solutions (United States)

Nelson Scarborough · Clinical Solutions

Clifford Herman

Abstract

Subcutaneous administration of microspheres releasing bupivacaine results in lower blood levels lasting for much longer times than those from bupivacaine solution.

Topics & Keywords

Anesthesia and Pain Management Advancements in Transdermal Drug Delivery Dental Anxiety and Anesthesia Techniques

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Anesthesia & Analgesia

Volume 120, Issue 1, pp. 36-44

DOI: 10.1213/ane.0000000000000507

Field-Weighted Citation Impact: 2.09