Inactivation of the DNA-Repair Gene<i>MGMT</i>and the Clinical Response of Gliomas to Alkylating Agents

20002,216 citationsJournal Articlebronze Open Access

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Methylation of the MGMT promoter in gliomas is a useful predictor of the responsiveness of the tumors to alkylating agents.

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Published in: New England Journal of Medicine

Volume 343, Issue 19, pp. 1350-1354

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