Comparison of Administration of Recombinant Human Thyrotropin with Withdrawal of Thyroid Hormone for Radioactive Iodine Scanning in Patients with Thyroid Carcinoma

1997469 citationsJournal Articlebronze Open Access

Authors

Paul W. Ladenson · Johns Hopkins University

Lewis E. Braverman

Ernest L. Mazzaferri · Mount Sinai Beth Israel

Françoise Brücker-Davis

David S. Cooper

Jeffrey R. Garber

Fredric E. Wondisford

Terry F. Davies · Mount Sinai Medical Center

Leslie J. DeGroot · University of Chicago Medical Center

Abstract

Thyrotropin stimulates radioiodine uptake for scanning in patients with thyroid cancer, but the sensitivity of scanning after the administration of thyrotropin is less than that after the withdrawal of thyroid hormone. Thyrotropin scanning is associated with fewer symptoms and dysphoric mood states.

Topics & Keywords

Thyroid Cancer Diagnosis and Treatment Thyroid Disorders and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 337, Issue 13, pp. 888-896

DOI: 10.1056/nejm199709253371304

Field-Weighted Citation Impact: 16.25