Rationalization of the Activity of Medical Ozone on Intervertebral Disc A Histological and Biochemical Study

Ozonetherapy is used for the treatment of immunodeficiency syndromes as well as for the treatment of cardiovascular disease. It is also used for the treatment of low back-pain with promising results although it is not yet well established. The aim of the current study is the presentation of the effects of ozonetherapy injected intradiscally or paravertebrally. We present the histological, immunological and biochemical changes in vertebral discs. Our material consist of human specimens as well as New Zealand rabbits.