Oxidative stress in patients affected by primary aldosteronism

201460 citationsJournal Article

Authors

Luigi Petramala · Asociación Colombiana de Nefrología e Hipertensión Arterial

Pasquale Pignatelli

Roberto Carnevale

Laura Zinnamosca · Asociación Colombiana de Nefrología e Hipertensión Arterial

C. Marinelli · Asociación Colombiana de Nefrología e Hipertensión Arterial

Amina Settevendemmie · Asociación Colombiana de Nefrología e Hipertensión Arterial

Antonio Concistrè · Asociación Colombiana de Nefrología e Hipertensión Arterial

Abstract

This is the first study showing an increased oxidative stress in primary aldosteronism, characterized by increased serum levels of Nox2-dp and urinary excretion of isoprostanes. After APA removal with laparoscopic adrenalectomy, we found reduction of serum Nox2-dp and urinary isoprostanes.

Topics & Keywords

Hormonal Regulation and Hypertension Adrenal Hormones and Disorders Adrenal and Paraganglionic Tumors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Hypertension

Volume 32, Issue 10, pp. 2022-2029

DOI: 10.1097/hjh.0000000000000284

Field-Weighted Citation Impact: 4.72