Dissection and Comparative Anatomy of the Origins of Replication of Lambdoid Phages

197964 citationsJournal Article

Authors

David D. Moore · RF Laboratories (United States)

Katherine Denniston-Thompson · University of Wisconsin–Madison

Karen Krüger · RF Laboratories (United States)

M. E. Furth · National Cancer Institute

Bill G. Williams · University of Wisconsin–Madison

Donna L. Daniels · National Cancer Institute

Frederick R. Blattner

Abstract

Bacteriophage λ DNA replication begins at a unique origin region located near position 40,000 on the 50,000-bp-long λ DNA molecule. A map of this region is shown in Figure 1. Initiation leads to formation of a pair of replication forks which proceed in both directions away from the origin region.

Topics & Keywords

Bacteriophages and microbial interactions Bacterial Genetics and Biotechnology Evolution and Genetic Dynamics

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Cold Spring Harbor Symposia on Quantitative Biology

Volume 43, Issue 0, pp. 155-163

DOI: 10.1101/sqb.1979.043.01.022