Cushing's Syndrome in Children and Adolescents -- Presentation, Diagnosis, and Therapy

1994432 citationsJournal Articlebronze Open Access

Authors

Maria Alexandra Magiakou · Eunice Kennedy Shriver National Institute of Child Health and Human Development

George Mastorakos

Edward H. Oldfield

María Teresa Gómez-Hernández

Abstract

Weight gain and growth retardation are common clinical characteristics of Cushing's syndrome in children and adolescents. Diagnostic evaluation of such patients with CRH stimulation alone and combined with inferior petrosal sinus sampling and imaging studies is accurate, and therapy is usually successful.

Topics & Keywords

Pituitary Gland Disorders and Treatments Adrenal Hormones and Disorders Adrenal and Paraganglionic Tumors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 331, Issue 10, pp. 629-636

DOI: 10.1056/nejm199409083311002

Field-Weighted Citation Impact: 8.10