Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

19966,327 citationsJournal Article

Authors

Robert V. Considine

Madhur K. Sinha

Mark L. Heiman · Eli Lilly (United States)

Aidas Kriauciunas · Eli Lilly (United States)

Thomas W. Stephens · Eli Lilly (United States)

Mark R. Nyce

Joanna P. Ohannesian

Cheryl Marco

Linda J. McKee · Cancer Research And Biostatistics

Abstract

Serum leptin concentrations are correlated with the percentage of body fat, suggesting that most obese persons are insensitive to endogenous leptin production.

Topics & Keywords

Regulation of Appetite and Obesity Biochemical Analysis and Sensing Techniques Adipokines, Inflammation, and Metabolic Diseases

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: New England Journal of Medicine

Volume 334, Issue 5, pp. 292-295

DOI: 10.1056/nejm199602013340503

Field-Weighted Citation Impact: 86.12