Effect of High-Dose Ibuprofen in Patients with Cystic Fibrosis

1995734 citationsJournal Articlebronze Open Access

Authors

Michael W. Konstan · Case Western Reserve University

Pamela J. Byard · Rainbow Babies & Children's Hospital

Charles L. Hoppel · Case Western Reserve University

Pamela B. Davis · Case Western Reserve University

Abstract

In patients with cystic fibrosis and mild lung disease, high-dose ibuprofen, taken consistently for four years, significantly slows the progression of the lung disease without serious adverse effects.

Topics & Keywords

Cystic Fibrosis Research Advances Asthma and respiratory diseases Pneumocystis jirovecii pneumonia detection and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 332, Issue 13, pp. 848-854

DOI: 10.1056/nejm199503303321303

Field-Weighted Citation Impact: 35.32