Immediate Hormonal Therapy Compared with Observation after Radical Prostatectomy and Pelvic Lymphadenectomy in Men with Node-Positive Prostate Cancer

19991,200 citationsJournal Article

Authors

Edward M. Messing · University of Rochester Medical Center

Judith Manola · Dana-Farber Cancer Institute

Michael Sarosdy · The University of Texas at San Antonio

George Wilding

E. David Crawford · University of Colorado Health

Donald L. Trump · UPMC Hillman Cancer Center

Abstract

Immediate antiandrogen therapy after radical prostatectomy and pelvic lymphadenectomy improves survival and reduces the risk of recurrence in patients with node-positive prostate cancer.

Topics & Keywords

Prostate Cancer Diagnosis and Treatment Prostate Cancer Treatment and Research Phytoestrogen effects and research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 341, Issue 24, pp. 1781-1788

DOI: 10.1056/nejm199912093412401

Field-Weighted Citation Impact: 46.41