Genome‐Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture

2015163 citationsJournal Articlegreen Open Access

Authors

Marta E. Alarcón‐Riquelme · Oklahoma Medical Research Foundation

Julie T. Ziegler · Wake Forest University

Julio E. Molineros · Oklahoma Medical Research Foundation

Timothy D. Howard · Wake Forest University

Andrés Moreno‐Estrada · Stanford University

Elena Sánchez · Icahn School of Medicine at Mount Sinai

Hannah C. Ainsworth

Abstract

Our results demonstrate that studying admixed populations provides new insights in the delineation of the genetic architecture that underlies autoimmune and complex diseases.

Topics & Keywords

Systemic Lupus Erythematosus Research Atherosclerosis and Cardiovascular Diseases T-cell and B-cell Immunology

UN Sustainable Development Goals

Sustainable cities and communities

Publication Details

Published in: Arthritis & Rheumatology

Volume 68, Issue 4, pp. 932-943

DOI: 10.1002/art.39504

Field-Weighted Citation Impact: 11.79