Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

2016185 citationsJournal Articlebronze Open Access

Authors

Jennifer S. Yokoyama · University of California, San Francisco

Yunpeng Wang · Washington University in St. Louis

Andrew J. Schork · University of California, San Diego

Wesley K. Thompson · University of California, San Diego

Celeste M. Karch · Washington University in St. Louis

Carlos Cruchaga · Washington University in St. Louis

Linda K. McEvoy

Abstract

Our findings demonstrate genetic overlap between AD and immune-mediated diseases and suggest that immune system processes influence AD pathogenesis and progression.

Topics & Keywords

Tryptophan and brain disorders Diabetes and associated disorders Alzheimer's disease research and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Neurology

Volume 73, Issue 6, pp. 691-691

DOI: 10.1001/jamaneurol.2016.0150

Field-Weighted Citation Impact: 6.72