Paroxysmal Nocturnal Hemoglobinuria with Onset in Childhood and Adolescence

1991157 citationsJournal Article

Authors

Russell E. Ware · Duke University Hospital

Abstract

Children and adolescents with PNH have a greater prevalence of bone marrow failure than do adults with this disorder, and their morbidity and mortality are high. Bone marrow transplantation should be considered for selected young patients with PNH.

Topics & Keywords

Complement system in diseases Blood groups and transfusion

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 325, Issue 14, pp. 991-996

DOI: 10.1056/nejm199110033251403

Field-Weighted Citation Impact: 1.91