The T-box transcription factor TBX3 drives proliferation by direct repression of the p21WAF1 cyclin-dependent kinase inhibitor

201634 citationsJournal Articlegold Open Access

Authors

Tarryn Willmer · University of Cape Town

Abstract

Results from this study provide a detailed mechanism of how TBX3 transcriptionally represses p21(WAF1) which adds to our understanding of how it may contribute to oncogenesis.

Topics & Keywords

Congenital heart defects research Genomic variations and chromosomal abnormalities Cancer-related Molecular Pathways

Publication Details

Published in: Cell Division

Volume 11, Issue 1, pp. 6-6

DOI: 10.1186/s13008-016-0019-0

Field-Weighted Citation Impact: 2.96

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The T-box transcription factor TBX3 drives proliferation by direct repression of the p21WAF1 cyclin-dependent kinase inhibitor

Authors

Abstract

Topics & Keywords

Publication Details