Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

19912,166 citationsJournal Articlebronze Open Access

Authors

Robert Clarke · Tallaght University Hospital

Leslie Daly · University College Dublin

Killian Robinson · Trinity College Dublin

E. R. Naughten · National Children’s Research Centre

S. F. Cahalane · National Children’s Research Centre

Brian Fowler

Ian Graham · Trinity College Dublin

Abstract

Hyperhomocysteinemia is an independent risk factor for vascular disease, including coronary disease, and in most instances is probably due to cystathionine beta-synthase deficiency.

Topics & Keywords

Folate and B Vitamins Research Metabolism and Genetic Disorders Iron Metabolism and Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 324, Issue 17, pp. 1149-1155

DOI: 10.1056/nejm199104253241701

Field-Weighted Citation Impact: 49.37