A Systems BIOlogy Study to TAilored Treatment in Chronic Heart Failure: Rationale, Design, and Baseline Characteristics of BIOSTAT-CHF

2016201 citationsJournal Articlegreen Open Access

Authors

Adriaan A. Voors · Hanze University of Applied Sciences

Stefan D. Anker · University of Göttingen

John G.F. Cleland · Harefield Hospital

Kenneth Dickstein · University of Stavanger

Gerasimos Filippatos · University General Hospital Attikon

Pim van der Harst · University Medical Center Groningen

Hans L. Hillege

Abstract

By using a novel systems biology approach, incorporating demographics, biomarkers, genome-wide analysis, and proteomics, a model that predicts response to therapy will be developed, which should be instrumental in developing alternative therapies for patients with suboptimal response to currently recommended therapies and thus further improve care for patients with heart failure.

Topics & Keywords

Heart Failure Treatment and Management Cardiovascular Function and Risk Factors Cardiac pacing and defibrillation studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Journal of Heart Failure

Volume 18, Issue 6, pp. 716-726

DOI: 10.1002/ejhf.531

Field-Weighted Citation Impact: 12.33