A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

2015354 citationsJournal Articlebronze Open Access

Authors

Katie Ewer · Oxford Biomedical Research

Tommy Rampling · National Institute for Health Research

Navin Venkatraman · Oxford Biomedical Research

Georgina Bowyer · National Institute for Health Research

Daniel Wright · Oxford Biomedical Research

Teresa Lambe · Oxford Biomedical Research

Egeruan B. Imoukhuede

Abstract

The ChAd3 vaccine boosted with MVA elicited B-cell and T-cell immune responses to ZEBOV that were superior to those induced by the ChAd3 vaccine alone. (Funded by the Wellcome Trust and others; ClinicalTrials.gov number, NCT02240875.).

Topics & Keywords

Viral Infections and Outbreaks Research Viral Infections and Vectors Hepatitis B Virus Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 374, Issue 17, pp. 1635-1646

DOI: 10.1056/nejmoa1411627

Field-Weighted Citation Impact: 34.17